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          2. 中文 | English
             
            Test for reproductive toxicity
            Test for in vitro cytotoxicity
            Test for sensitization
            Test for irritation
            Tests for systemic toxicity
            Pyrogenicity test
            Test for genotoxicity
            Test for carcinogenicity
            Test for local effects after implantation
            Tests for interactions with blood
            Immunotoxicity test
            Bio-degrade test
            Contact

            Address: 201-301, Building 2, № 427 Jumen Road, Shanghai, China

            Zip code: 200023

            Tel: 0086-21-63034903

            Fax: 0086-21-63011643

            Contact person: Zhewei Huang

            Emailbiomatercenter@163.com

             
                Home > Business > Test for genotoxicity
            Test for genotoxicity

                The primary function of genotoxicity tests is to inverstigate,using test cells or organisms, the potential of products to induce genetic changes in man that may be transmitted via the germ cells to future generations. Scientific data generally support the hypothesis that DNA damage in somatic cells is a critical event in the initiation of cancer. Such damage can result in mutations, and tests to detect genotoxic activity may also identify chemicals that have the potential to lead to carcinogenesis. Thus, some of the tests are useful for the inverstigation of putative carcinogenic activity.

            Methods of test for genotoxicity including:

            In vitro mammalian chromosome aberration test,

            Salmonella typhimurium reverse mutation assay,

            In vitro mammalian cell gene mutation test,

            Micronucleus test of bone marrow cell

             

             

                                                        

             

             

             

            Up:Pyrogenicity test

            Down:Test for carcinogenicity

             

             

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